GroPI(4,5)P2

Product Number: P-4500

$122.00$644.00

$122.00
$373.00
$644.00
SKU: P-4500- Category: Tags: , ,

Glycerophosphoinositol 4,5-diphosphate (GroPI(4,5)P2) is a synthetic, purified PI(4,5)P2 without acyl chains at the 1- and 2-positions of the glycerol.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues and is also a substrate for class I phosphoinositide 3-kinase (PI3-K).

Bulk discounts available, please email echelon@echelon-inc.com for information.

Categories

Lipids

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Glycerolphosphoinositide, Phosphoinositides

CAS Number

111188-72-8

Molecular Formula

C9H16Na5O17P3

Molecular Weight (g/mol)

604.10

Purity

>95%

Storage

-20 °C or below

Technical Data Sheet

1) Zizza, P., C. Iurisci, et al. (2012). “Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity.” J Biol Chem 287(20): 16849-16859.

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