BODIPY TMR PI(4,5)P2

Product Number: C-45M6

$413.00$710.00

$413.00
$710.00

BODIPY TMR PI(4,5)P2 (BODIPY TMR Phosphatidylinositol 4,5-bisphosphate) is a water soluble analog of PI(4,5)P2 (PIP2) labeled with the orange fluorophore, Bodipy®-TMR, at the sn-1 position.


Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3.

Excitation/Emission

542/574 nm

Storage

-20 °C, protect from light

Publications

1) Cabanos C, Wang M, Han X, Hansen SB (2017) A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Rep 20(6):1287–1294

Bulk discounts available, please email echelon@echelon-inc.com for information.


Categories

Lipids

Filter

Fluorescent, Phosphoinositides, PI(4,5)P2

Excitation/Emission

542/574 nm

Molecular Formula

C78H147BF2N9O22P3

Molecular Weight (g/mol)

1,704.78

Purity

>95%

Storage

-20 °C or below, protect from light

Technical Data Sheet

Scroll to Top