Atrial Natriuretic Peptide (1-28), rat

CAS Number: 88898-17-3
Molecular Weight: 3062.5
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH [Cys7-Cys23]
Sequence (1-letter): SLRRSSCFGGRIDRIGAQSGLGCNSFRY-OH
Storage: -20 °C or below

Atrial Natriuretic Peptide (ANP) is a cardiovascular hormone which is synthesized in cardiac muscular cells. It is released in response to stretching of atrial walls, Endothelin, and stimulation of β-adrenoreceptors. ANP increases renal sodium excretion resulting in decreased expanded extracellular fluid volume (ECF). ANP is degraded by neutral endopeptidase (NEP). This is the major circulating form of ANP in rats.