Molecular Weight: 1595.78
Salt Form: TFA
Sequence (3-letter): Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Cys-NH2 [Cys4-Cys15]
Sequence (1-letter): RSSCFGGRIDRIGAC-NH2
Storage: -20 °C or below
Atrial Natriuretic Peptide (ANP) Des[18-22] (4-23) amide, rat is a selective agonist of natriuretic peptide receptor subtype C (NPR-C). ANP is a cardiovascular hormone which is synthesized in cardiac muscular cells. It is released in response to stretching of atrial walls, Endothelin, and stimulation of β-adrenoreceptors. ANP increases renal sodium excretion resulting in decreased expanded extracellular fluid volume (ECF). ANP is degraded by neutral endopeptidase (NEP).