Amyloid Blocker

CAS Number: 189064-06-0
Molecular Weight: 821.48
Salt Form: TFA
Purity: >96%
Sequence (3-letter): Ac-Gln-Lys-Leu-Val-Phe-Phe-NH2
Sequence (1-letter): Ac-QKLVFF-NH2
Storage: -20 °C or below

Amyloid Blocker (Acetyl-Amyloid b-Protein (15-20) amide) can bind specifically to the homologous region in Beta Amyloid (Aβ). Peptides containing the sequence KLVFF can bind specifically to this region in Aβ and can prevent full length amyloid fibril formation.

References

Lin SY, Chu HL (2003) “Fourier transform infrared spectroscopy used to evidence the prevention of beta-sheet formation of amyloid beta(1-40) peptide by a short amyloid fragment”. Int J Biol Macromol. 32(3-5):173-7.