Molecular Weight: 661.26
Salt Form: N/A
Sequence (3-letter): Ac-Val-Glu-Thr-Asp-AMC
Sequence (1-letter): Ac-VETD-AMC
Storage: -20 °C or below
Ac-Val-Glu-Thr-Asp-AMC is a fluorogenic substrate for Caspase 8. Caspase 8 is a cysteine protease involved in apoptosis induced by Fas and other stimuli.
Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.