Ac-Leu-Glu-Val-Asp-AMC (Caspase 4 Substrate)

Product Number: 860-49


SKU: 860-49 Category: Tags: ,

Molecular Weight: 673.3
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Ac-Leu-Glu-Val-Asp-AMC
Sequence (1-letter): Ac-LEVD-AMC
Storage: -20 °C or below

Ac-Leu-Glu-Val-Asp-AMC is a fluorogenic substrate for Caspase 4. Caspase 4 is a cysteine protease with a poorly defined role in the caspase family. Recent studies have shown it to have a role in inflammation and innate immunity. Like all caspases it cleaves at the Asp residue and prefers the sequence Leu-Glu-Val-Asp.

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

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Caspase, Enzyme Substrates

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