Ac-Leu-Glu-Val-Asp-AMC (Caspase 4 Substrate)

Product Number: 860-49

$130.00$487.00

$130.00
$487.00
SKU: 860-49 Category: Tags: ,

Molecular Weight: 673.3
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Ac-Leu-Glu-Val-Asp-AMC
Sequence (1-letter): Ac-LEVD-AMC
Storage: -20 °C or below

Ac-Leu-Glu-Val-Asp-AMC is a fluorogenic substrate for Caspase 4. Caspase 4 is a cysteine protease with a poorly defined role in the caspase family. Recent studies have shown it to have a role in inflammation and innate immunity. Like all caspases it cleaves at the Asp residue and prefers the sequence Leu-Glu-Val-Asp.

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com

 

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