Ac-Ile-Glu-Pro-Asp-AFC (Granzyme B Substrate)

Product Number: 863-30


SKU: 863-30 Category: Tags: ,

Molecular Weight: 725.25
Salt Form: N/A
Purity: >96%
Sequence (3-letter): Ac-Ile-Glu-Pro-Asp-AFC
Sequence (1-letter): Ac-IEPD-AFC
Storage: -20 °C or below

Ac-Ile-Glu-Pro-Asp-AFC is a fluorogenic substrate for Granzyme B. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates several caspases involved in apoptosis.

Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

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Caspase, Enzyme Substrates

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