Product Number: L-9418


SKU: L-9418- Category: Tags: ,

OMPT is a metabolically-stabilized analog of Lysophosphatidic Acid (LPA) which acts as potent agonist for the LPA3 receptor. Of the two enantiomers, (2S)-OMPT is more potent than (2R)-OMPT showing 5-20 fold more activity in calcium release from LPA3-transfected Sf9 and rat hepatoma Rh7777 cells. (2S)-OMPT is also more potent in inducing calcium release, IL-6 production, and MAPK and Akt phosporylation in OVCAR3 cells.


-20 °C

Alternate Name: L-sn-1-O-oleoyl-2-O-methylglyceryl-3-phosphothionate

Featured in Publications

1) Lin, D. A. and J. A. Boyce (2005). “IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells.” J Immunol 175(8): 5430-8.
2) Zhao, C., M. J. Fernandes, et al. (2008). “Regulation of lysophosphatidic acid receptor expression and function in human synoviocytes: implications for rheumatoid arthritis?” Mol Pharmacol 73(2): 587-600.
3) Qian, L., Y. Xu, et al. (2003). “Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity.” J Med Chem 46(26): 5575-8.


Technical Data Sheet

We are in the process of migrating our technical data sheets (TDS) to this space. They can currently be found in the description section of the product pages. Thank you for your patience. For any technical questions, please contact us at echelon@echelon-inc.com



Biochemical Reagents


Agonist, Lysophosphatidic Acid, Lysophospholipid

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