Hyaluronic Acid (HA) is a well established part of the extracellular matrix (ECM) and is known to participate in cell adhesion and cell-to-cell communication. It has been implicated in the development of cancer and cardiovascular disease.
Lipids have emerged as complex players in cellular signaling, membrane trafficking, and are increasingly investigated as potential therapeutic targets. EBI carries a wide selection of lipid antibodies that have been validated across a range of applications.
Echelon carries five PIP Mass ELISA kits that can measure the relative levels of 5 different PIPs. Each PIP Mass ELISA uses a protocol for the extraction of phosphoinositides (PIPs) from millions of cells. Extractions are then analyzed using a competitive ELISA without the need for radioactivity
Lipids are fundamental building blocks for biological membranes and serve as intracellular signalling molecules through their influence on protein structure and function. EBI has developed a wide range of reagents for investigating lipid-protein interactions.
Lipid nanoparticles (LNP) have been in use for years as cellular transfection reagents. Interest in novel forms of LNPs grew rapidly after their inclusion as part of the mRNA vaccines for SARS-CoV-2 and their applications are still being widely explored.
Exosomes have have rapidly gained scientific attention due to their ability to transfer protein and nucleic acid cargo between cells. EBI’s ExoClean and ExoTracker kits offer researchers a simple system for labeling and purifying exosomes in a time and cost-effective manner.
Peptides are short chains of amino acids similar to proteins that have a wide array of biological functions. Aberrant peptide forms have been implicated in a number of diseases while novel, synthetic peptides constitute a rapidly growing area of drug discovery.