Inositol 1,4,5-trisphosphate (Ins(1,4,5)P3)

Catalog No.:  Q-0145
MW: 551.99
CAS: 108340-81-4

Description:  Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,4,5-trisphosphate (IP3) is a second messenger produced by phospholipase C catalyzed hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2). IP3 binds to the IP3-receptor on the endoplasmic reticulum causing calcium to be released through the opening of a tetrameric ion channel. IP3 is rapidly metabolized by a specific series of inositol phosphatases and kinases.


-20 °C


"Phosphatidylinositol and inositol phosphate metabolism." J. Cell Sci. 2001, 114, 2207-8.

Product Keywords: D-myo-Inositol 1,4,5-trisphosphate, Ins(1,4,5)P3, I(1,4,5)P3, or IP3

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Options/Sizes Pricing
Q-0145-100ug $ 34.00
Q-0145-500ug $ 63.00
Q-0145-1mg $ 113.00
Additional Information:
Tech Data Sheet - Q-0145

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assay and reagents for drug discovery in lipid signaling pathways