Lysophosphatidic Acid (LPA) is a serum-derived phospholipid involved in diverse cellular processes such as cell proliferation, chemotaxis, platelet aggregation, wound healing, angiogenesis, tumor invasion, and smooth muscle contraction. Recent research indicates LPA may play a significant role in the pathophysiology of cancer and may be used as a biomarker for ovarian cancer. (several literature citations indicate plasma LPA levels are elevated in ovarian cancer patients). The Echelon LPA assay service uses a sensitive and robust method for the quantification of LPA in a 96-well plate format. The LPA assay was co-developed using the proprietary monoclonal antibody of Lpath Inc. (San Diego, CA. www.lpath.com).

**We currently do not suggest the use of this kit for the detection of LPA in rodent samples**