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       Category : Phosphoinositide Reagents and Derivatives :   Metabolically Stabilized Phosphoinositides : PtdIns(5)P 5-methylenephosphonate



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PtdInsPns compounds are employed as substrates for kinases, phosphatases and binding proteins as described in many publications. 5C-PtdIns(5)P is resistant to enzymatic hydrolysis at the 5-position and may demonstrate unique biological function due to the varied chemical structure compared to the natural analog. 5C-PtdIns(5)P showed similar affinity for the tumor suppressor protein ING2 as PtdIns(5)P and augmented cell death induced by a DNA double-strand break in HT1080 cells.

MW :
—619.5
Formula:
—C18H43N3O16P2
Solubility:
—H2O, 2 mg/mL,
 
Additional Informaiton
  --
P-5C04