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Product Name
PI3-K alpha Inhibitor 2
Catalog Number
B-0304
Unit Price
$45.00
Quantity
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| 3-(4-Morpholinothieno[3,2-d]pyrimidin-2-yl)phenol is a selective inhibitor for the a-isoform of PI 3-Kinase (IC50: PI 3-Kα = 2 nM, PI 3-Kβ = 16 nM, PI3-Kγ = 660 nM, PI3KC2β = 220 nM)). It showed >1000-fold selectivity vs. protein kinases such as PKA, KDR, PKCa, and E/CDK2 (IC50 = 91, 3.4, 466, 288 uM). It inhibited proliferation of A375 melanoma cells at 580 nM.
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| Catalog: |
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—PI3-Kinase Inhibitors
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| Formula: |
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—C16H15N3O2S, FW: 313.4
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| Solubility: |
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—water: insoluble, DMSO: 10 mg/mL
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| Storage: |
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—store dry at 4oC. Stock solutions should be stored frozen (-20oC).
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| References: |
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—Bioorg. Med. Chem., 2006
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| Catalog: |
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—PI3-Kinase Inhibitors
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