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       Category : Enzymes :   Histone Deacetylase Enzymes : NCOR2/SMRT (2039066523)

2039066523

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DAD domain of human Nuclear Receptor Co-repressor 2 (NCOR2/SMRT, GenBank Accession No. NM_006312), amino acid 395-489 with N-terminal GST tag, MW = 39 kDa, expressed in E.coli system. NcoR2 is a transcriptional co-repressor that plays an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain (DAD) of NCOR2 is required for activation of the otherwise inert HDAC3 deacetylase.
Storage:
—Store product frozen at or below -70 ºC. Enzyme will be stable for at least 6 months at -70 ºC as undiluted stock. Freeze in working aliquots to avoid repeated thawing and freezing.
Catalog:
HDAC
 
Additional Informaiton
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E-D020G