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       Category : Phosphoinositide Reagents and Derivatives :   Metabolically Stabilized Phosphoinositides : PtdIns(3,4,5)P3 3-methylenephosphonate, diC8 (3C-PtdIns(3,4,5)P3 , diC8)



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Synthetic PI(3,4,5)3 analogs in which the 3-phosphate bond has been rendered metabolically stable as a phosphoithioate. P-3C916 increases sodium transport across monolayers of cells A6 through activation of GLUT4.

—Synthesis and Biological Activity of PTEN-Resistant Analogues of Phosphtidylinositol 3,4,5-triphosphate
— J. Am. Chem. Soc. 128, 16464-16465, 2006.
MW :
—959.8
Formula:
—C26H73N7O22P4
Solubility:
—H2O, 2 mg/mL
 
Additional Informaiton
  --
 P-C3908
 
 
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