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       Category : Phosphoinositide Reagents and Derivatives :   Metabolically Stabilized Phosphoinositides : 3-phosphothionate PI(3)P



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A synthetic phosphoinositide (3) phospate, PI(3)P, analog in which the 3-phosphate has been rendered metabolically stable as a phosphothionate. P-3S18 has been shown to bind to the FYVE domain and is a substrate for the 5-kinase, PIKfyve. Reference: J. Am. Chem. Soc., 128 (3), 885 -897, 2006. 10.1021/ja0554716 S0002-7863(05)05471-5, Chemical Synthesis and Molecular Recognition of Phosphatase-Resistant Analogues of Phosphatidylinositol-3-phosphate Y. Xu, S. Lee, T. G. Kutateladze, D. Sbrissa, A. Shisheva, and G. D. Prestwich http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2006/128/i03/abs/ja0554716.html
MW = :
—1010.2
Formula = :
—C45H93N3O15PS
 
Additional Informaiton
  --
P-3S18