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Product Name
Alkyl-OMPT
Catalog Number
L-9518
Unit Price
$206.00
Quantity
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| Alkyl-OMPT is a potent agonist for the seven transmembrane domain G-protein-coupled LPA 3 (lysophosphatidic Acid 3) receptors.
Long name: D-sn-1-O-0leyl-2-O-methyl-glyceryl-3-phosphothionate
Alkyl OMPT analogues induced cell migration in cancer cells mediated by activation of LPA1. Alkyl OMPT analogues also activated Ca2+ release via LPA2 activation but with reduced potency relative to sn-1-oleoyl LPA. In contrast, alkyl OMPT analogues were potent LPA3 agonists.(1)
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| Formula:: |
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—C22H44NaO5PS
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| FW:: |
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—474.6
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| References: |
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—(1)Biochem. Soc. Trans. (2005) 33, (1357-1361) Focus Topics at BioScience2005, New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors, G.D. Prestwich1, Y. Xu, L. Qian, J. Gajewiak and G. Jiang
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